Yes - You need to flash the ROM code to the D2000 before you use it - there is a pre-built ROM file included in the Intel System Studio for Microcontrollers application - Commercial Product Request - Intel® Products
This only needs to be done once. However the OTP bit is not set by default so you will be allowed to flash it again without issue.
This address is the start of the 32KB System Flash ..
/* Address of application's entry point */
#define ENTRY_POINT_ADDRESS ((void *)0x00180000)
You can refer to the D2000 DataSheet for the SOC memory map (Section 6.1.1) - Intel® Quark™ Microcontroller D2000: Datasheet