There is also a thread about something similar: Using ESRAM from user-space code. Did you already took a look at it?
I've read through the datasheet as well as the development guide but I'm not finding much. The problem I'm running into is that everyone is running programs on linux and I don't want to run linux at all. I would like to write this to run on bare metal, otherwise I'll end up trashing the OS while doing the memory check. I haven't been able to find any sort of example on writing any sort of simple application or basic OS to run on the Quark