I am running a MSI mobo with the Windows 10 Preview.
I am not really having too much of an issue that I know of. Basically, I am installing the drivers using the disc that came with the mobo. Upon accessing the MSI Driver & Software Setup, I have installed everything, but no matter how many times I try, the Intel ME Drivers will not install. It says it has installed and to restart my PC, and nothing happens when I do that.
ME drivers work directly with the operating system and the BIOS of the motherboard, the version on the disk would most likely be for previous versions of Windows* and would not work with windows* 10. You would need to check when ME drivers would be available for windows 10* and these driver would need to be provided by MSI*