Yes it is possible, i did this on a DQ45CB, both boards use Intel Matrix Storage Manager, so it should be alright as well.
I tried several configurations:
like raid0, raid 1, raid 5, raid 10 etc.
Your configuration works fine for sure.
You will need to select the appropriate disk when creating the raid.
If you need help how to do it
Install Intel Storage Matrix Manager utility later. It will be very useful.
All the best,