Hello Binchen, thanks for contacting us through the Intel Communities.
I would need to get additional information on your issue. So please let me know what type of remote control are you using?
What kind of devices do you have connect to the USB?
It is important to let you know that we have tested our NUCs using a remote control, but we are able to turn the device ON only when it is on Standby or sleep mode.
We are using the infrared feature included on the D54250WYK NUC.