This happens because you need to apply the changes first and once this is done, the save profile button will become available.
The Graphics Controller HD 4000 supports OpenGL 4. You can check this information at the following link:
I recommend you checking with the software developer since our drivers do support the OpenGL feature.
Thanks, that solved the first problem
But for the OpenGL; for example, when running Quake 3 lightmaps seem to be missing. On Half-Life, it lags in large areas, and Quake 4 barely runs on minimum. (These are all OpenGL)
However, it runs fine with DirectX like Unreal Tournament on high settings
The graphics controller you have supports OpenGL 4. The feature is enabled by default at the driver level. My best recommendation is to contact the game developer to enable the OpenGL in the game.