We have not received reports on similar issues with this board. Due to this, you may want to contact out technical department for further assistance on your issue.
When you plug something into the USB ports, what does the BIOS show? Are they recognized? If the USB mouse and keyboard work, seems there is something different on those USBs not working, causing a conflict.
You could clear CMOS first and then try a BIOS Recovery:
Contact phone numbers for the different Support Centers available: http://www.intel.com/p/en_US/support/contact/phone