Restrospect Express HD can do it for you with no charge.
Have you installed the latest client software? Once you install it you should have a mapped network drive (normally X: or Y:) to \\<IP_of_SS4200-E>\Backups. Then run Restrospect Express HD and you should be able to backup.
Note you should map to a windows share, not FTP. iSCSI is not required.
Now my other laptop failed and i have moved to latest Intel and Windows 7 64 bit laptop.
I am unable to install the software you have suggested on windows 7, 64 bit laptop.
Stared using FBackup 4 on Win7.