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Dividing the drive in different partitions it’s not recommended and actually, it’s not a supported configuration for the Intel® Optane™ Memory, especially if you are planning to install another OS in the drive.
I recommend you to keep using your drive with one single partition so the Intel® Optane™ Memory can keep working correctly.
I hope this information answers your question. Please let me know if there is anything else I can help you.
Have a nice day.