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I understand that you cannot setup the Intel® Optane™ Memory and you have make sure that every single configuration at BIOS and OS level is properly set. According to what I have seen so far in regards to the Intel® Optane™ Memory setup process is that when the enable button is greyed out is because it is not recognized as an NVMe* device. That could be fixed by installing the RST driver - which you have done already - or by connecting the module to another M.2 slot.
I checked the motherboard’s specifications website (let me know if that’s not the correct one) and there is a note regarding to the M.2 slots: https://www.asrock.com/mb/Intel/Fatal1ty%20Z270%20Gaming%20K6/index.asp#Specification. Usually these ports are shared with the SATA ports and when both ports have devices connected at the same time, one of them doesn’t work properly. This can be fixed by changing the port (M.2 or SATA) and connect the device to another port. It’s easier to just connect the Intel® Optane® Memory to the other M.2 slot, so please try this and check if this time you can enable the module from the application.
I hope this works.
Have a nice day.