This message was posted on behalf of Intel Corporation
Thanks for posting in our community. We understand that you would like to use the Bluetooth* features of Intel® Wireless-AC 9260.
Please notice that this forums are focused on end-user level support. As you mentioned, this device Bluetooth* portion works through the USB interface on the M.2 connector, but we can't confirm if it would be possible to use a custom interface to connect the adapter to the motherboard USB interface directly.
If you require Bluetooth* 5.0 capability on a branded PC/laptop, please contact the OEM (Original Equipment Manufacturer) for options. If this is for a new system you're designing, please refer to your distributor or our Resource and Design Center: