Computer: NUC7i5BNK, BIOS and drivers are up to date.
Operating System: Windows 10 Home, 64 bit, all updates installed and no Silicon Labs drivers are installed.
The main use of this computer involves a USB connection to other equipment. The manufacturer provides a link to Silicon Labs to download CD-301501-003.zip. When unzipped, I ran CP210xVCPInstaller_64.exe, It runs but quickly aborts with the message "...unable to find any drivers designed for your machine." The other equipment was not connected as instructed by its manufacturer.
How do I get this driver installed?
I looked into the aforementioned CD Image and driver installer and everything that I can find is related to Windows XP or Windows 7; I can find no mention of support for Windows 10 (or even Windows 8/8.1, for that matter). This would explain why you are seeing the message indicating no drivers designed for your machine; there are no drivers designed for Windows 10.
I am not sure why you came to an Intel support forum asking questions about an add-on USB product. You should be talking to their support forum/people first...