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There are no chipset drivers to install. The chipset software package contains no drivers at all; it contains and installs a series of INF files that configure the standard Microsoft drivers to optimally support Intel processor and chipset features. The same applies for USB; the drivers are provided by Microsoft as part of Windows 10.
Could this be similar to the problem with Logitech 2.4GHz receiver and USB3: Wireless product not working properly when also using a USB 3.0 device - Logitech Support Article
This can be easily tested by using either an external USB hub or simple extension cord to put the kb/mouse receiver away from the USB3 ports. This can be a true problem since all ports are USB3 and very close to each other.
I'm using with my NUC6i5SYH Logitech wireless mouse and keyboard transmitting to Logitech Unified Receiver. Have no problems at all. I've updated receiver firmware with the latest version. In your case I recommend you to try to locate your receiver far from the NUC's USB port. Use for this USB cable extender.
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Regarding your chipset driver inquiry, Scott provided the correct answer. The Intel Chipset Device Software installs the Windows* INF files, which inform the operating system how to properly configure the chipset for specific functionalities, such as USB and core PCI. This description can be found in "Detail Description" of the driver download link.
Now in regard to you the connectivity issue, I would like to know the full model of your Microsoft Wireless Mouse and Keyboard.
All very helpful answers , many thanks to everyone . I purchased a 7 Port USB Hub , plugged in Microsoft receiver and all works well. The receiver is now some distance from the Nuc. Thanks for explaining the driver setup Scott , also many thanks Marjo for the link and info I'm sure the ultimate cause was interference.