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That’s is pretty cool device!
I checked the specifications and Graphics Input is USB-C (for optimum performance) or Mini DisplayPort using optional Wacom Link which seems totally compatible with Skull Canyon but Intel has not tested nor validated this device, here is the list of tested devices: http://www.intel.com/content/www/us/en/support/boards-and-kits/000020804.html
I also checked on the Wacom Community for any previous reference http://community.wacom.com/ but nothing, I would recommend that you post the same question to their community and I would also try checking with their support service.
I hope this helps,
This message was posted on behalf of Intel Corporation
My suggestion would be to contact Wacom for compatibility information. They may provide a list of tested hardware for their components.
Let's hope Wacom responds back with more information.