On the following link you will find all the drivers for your board, including the USB drivers:
Please try those drivers and also try a BIOS update on the board to the latest version, if you need assistance doing the BIOS update just get in contact directly with ASUS:
ASUS support site: https://www.asus.com/us/support/
ASUS phone number: 1-877-339-2787
Please let me know the results of installing the drivers above.
Any questions, please let me know.
Chipset drivers helped other issues, but not this one.
All is well now, an Audio Interface was causing the problem - no clue why
Thanks for the help,