You should be contacting ASUS support to determine if an ASUS graphics card is compatible with an ASUS motherboard, especially if you are going to spend that kind of money for a graphics card.
This message was posted on behalf of Intel Corporation
I agree with All's answer, the best support site to get this answered will be with the GPU manufacturer site.
That would be to make sure all the other components you have are going to work properly with the coming GPU.
Here the support site: http://www.nvidia.com/page/support.html
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