I've been finding that on our new Dell Latitudes and Optiplex desktops, if the PC has been off for an unknown amount of time or it's in standby, I can't successfully wake the computer. It looks like at some point the NIC shuts off, as the lights no longer show a link. An internal Dell document recommends disabling the EEE option, and that seems to have fixed it for standby, but enough time hasn't passed yet to test from off.
If this setting ends up being the problem, is it possible to disable it via script so I don't have to touch all of our systems? I checked PROsetcl, and it doesn't appear to be listed.