Im using Windows 7 premium on my netbook, Every time i try to log in to IntelAppup(SM) centre, it gives me an Error code of 106, saying we are unable to process your request, the Intel Appup server may be down.
I was using Spywaredoctor as antivirus but even after disabling it the problem still persists.
This may be an issue with your firewall.
Please see "firewall" here: http://appdeveloper.intel.com/en-us/blog/2010/01/19/what-check-when-appup-wont-launch
Technical Support Team
Intel AppUp(SM) Developer Program
Intel AppUp(SM) Center